Many months after their war with a rogue group of Inhumans, the team is still reeling. Coulson is again trying to put the pieces of his once revered organization back together while also dealing with the loss of his hand. His confidante and second in command, Agent Melinda May, has yet to return from an impromptu vacation with ex-husband Andrew; deadly superspy Agent Bobbi Morse is recovering from her traumatic torture at the hands of Grant Ward; Fitz is obsessed with discovering the truth behind the mysterious disappearance of Simmons; and all are on high-alert for the next move from Ward and Hydra.
When Coulson and the team discover a new Inhuman, S.H.I.E.L.D. comes face to face with another organization searching for powered people. And still reeling from Simmons' dramatic disappearance, Fitz goes to extreme lengths to try to learn how to get her back.
Daisy, Mack and Coulson race to protect Lincoln as Rosalind's team hunts down the Inhuman in their quest for powered people. Meanwhile, Hunter proves that there is no line that he will not cross to exact his revenge against Ward and Hydra.
Having reluctantly agreed to share information with Rosalind and the ATCU, Coulson and the team go in search for the Inhuman who is killing off other Inhumans, and May feels that Hunter's mission to take down Ward is getting too personal.
The stakes get even higher as Hunter and May continue to go after Ward and Hydra, and Daisy and Coulson begin to suspect that the ATCU may be keeping a big secret from S.H.I.E.L.D., on "Marvel's Agents of S.H.I.E.L.D."
As Daisy and the team fight to protect Inhumans, S.H.I.E.L.D. discovers the shocking truth about one of their biggest foes. Meanwhile, Fitz helps Simmons recover information that could lead them back through the portal.
S.H.I.E.L.D. and Hydra go head-to-head in a battle that will change Coulson's world forever. While Daisy and her team of Inhumans fight to keep Hydra at bay, Coulson and Fitz take the ultimate risk, in the epic winter finale.
When a radical group called The Watchdogs emerges with plans to eliminate the Inhumans, Agent Mack and his brother get caught in the crossfire. Meanwhile, Simmons discovers a powerful chemical compound that could alter the future for Inhumans.
Agent Daisy Johnson must call upon the Secret Warriors for an inaugural mission that will leave no member unscathed. Meanwhile, S.H.I.E.L.D. learns more about Hive's powers, forcing them to question everyone they trust.
Following the events of Marvel's Captain America: The Winter Soldier, S.H.I.E.L.D. was forever changed. Forced to operate in the shadows, Director Phil Coulson and his team raced against Hydra in search of an alien city, encountered "The Real S.H.I.E.L.D.," and faced off against a group of Inhumans. Before you gear-up for Season 3, catch-up on some of the biggest moments from Season 2.