As the world comes to grips with the existence of superheroes and aliens, agent Phil Coulson assembles a small group of highly skilled agents; the team's first assignment is to find a man with extraordinary -- and potentially devastating -- powers.
With Colonel Glenn Talbot now on their trail, Coulson and his team seek refuge in the last place anyone would look, where they begin to uncover S.H.I.E.L.D.'s most dangerous secrets--secrets that could destroy them all.
Just when there's no one left to trust, Agent Maria Hill (Cobie Smulders)--from "Marvel's The Avengers" and "Marvel's Captain America: The Winter Solider"--returns to team up with Coulson as S.H.I.E.L.D. is being destroyed around them.